Showing posts with label Sugar. Show all posts
Showing posts with label Sugar. Show all posts

Saturday, 1 May 2021

Cheap, Legal And Everywhere: How Food Companies Get Us 'Hooked' On Junk

Junk Food 

 

 



Saturday, 3 April 2021

Sugar not so nice for your child’s brain development

Sugar not so nice for your child’s brain development

New research led by a University of Georgia faculty member in collaboration with a University of Southern California research group has shown in a rodent model

 


 Photo by Brett Jordan on Unsplash

 

Newswise — Sugar practically screams from the shelves of your grocery store, especially those products marketed to kids.

Children are the highest consumers of added sugar, even as high-sugar diets have been linked to health effects like obesity and heart disease and even impaired memory function.

However, less is known about how high sugar consumption during childhood affects the development of the brain, specifically a region known to be critically important for learning and memory called the hippocampus.

New research led by a University of Georgia faculty member in collaboration with a University of Southern California research group has shown in a rodent model that daily consumption of sugar-sweetened beverages during adolescence impairs performance on a learning and memory task during adulthood. The group further showed that changes in the bacteria in the gut may be the key to the sugar-induced memory impairment.

Supporting this possibility, they found that similar memory deficits were observed even when the bacteria, called Parabacteroides, were experimentally enriched in the guts of animals that had never consumed sugar.

“Early life sugar increased Parabacteroides levels, and the higher the levels of Parabacteroides, the worse the animals did in the task,” said Emily Noble, assistant professor in the UGA College of Family and Consumer Sciences who served as first author on the paper. “We found that the bacteria alone was sufficient to impair memory in the same way as sugar, but it also impaired other types of memory functions as well.”

Guidelines recommend limiting sugar

The Dietary Guidelines for Americans, a joint publication of the U.S. Departments of Agriculture and of Health and Human Services, recommends limiting added sugars to less than 10 percent of calories per day.

Data from the Centers for Disease Control and Prevention show Americans between the ages 9-18 exceed that recommendation, the bulk of the calories coming from sugar-sweetened beverages.

Considering the role the hippocampus plays in a variety of cognitive functions and the fact the area is still developing into late adolescence, researchers sought to understand more about its vulnerability to a high-sugar diet via gut microbiota.

Juvenile rats were given their normal chow and an 11% sugar solution, which is comparable to commercially available sugar-sweetened beverages.

Researchers then had the rats perform a hippocampus-dependent memory task designed to measure episodic contextual memory, or remembering the context where they had seen a familiar object before.

“We found that rats that consumed sugar in early life had an impaired capacity to discriminate that an object was novel to a specific context, a task the rats that were not given sugar were able to do,” Noble said.

A second memory task measured basic recognition memory, a hippocampal-independent memory function that involves the animals’ ability to recognize something they had seen previously.

In this task, sugar had no effect on the animals’ recognition memory.

“Early life sugar consumption seems to selectively impair their hippocampal learning and memory,” Noble said.

Additional analyses determined that high sugar consumption led to elevated levels of Parabacteroides in the gut microbiome, the more than 100 trillion microorganisms in the gastrointestinal tract that play a role in human health and disease.

To better identify the mechanism by which the bacteria impacted memory and learning, researchers experimentally increased levels of Parabacteroides in the microbiome of rats that had never consumed sugar. Those animals showed impairments in both hippocampal dependent and hippocampal-independent memory tasks.

“(The bacteria) induced some cognitive deficits on its own,” Noble said.

Noble said future research is needed to better identify specific pathways by which this gut-brain signaling operates.

“The question now is how do these populations of bacteria in the gut alter the development of the brain?” Noble said. “Identifying how the bacteria in the gut are impacting brain development will tell us about what sort of internal environment the brain needs in order to grow in a healthy way.”

The article, “Gut microbial taxa elevated by dietary sugar disrupt memory function,” appears in Translational Psychiatry. Scott Kanoski, associate professor in USC Dornsife College of Letters, Arts and Science, is corresponding author on the paper.

Additional authors on the paper are Scott Kanoski, Elizabeth Davis, Linda Tsan, Clarissa Liu, Andrea Suarez and Roshonda B. Jones from the University of Southern California; Christine Olson, Yen-Wei Chen, Xia Yang and Elaine Y. Hsiao from the University of California-Los Angeles; and Claire de La Serre and Ruth Schade from UGA.

 


This release is available online at https://news.uga.edu/sugar-not-so-nice-childs-brain-development/


 

Sunday, 22 November 2020

What Happens to Your Body When You Stop Eating Sugar

Sugar 

 

 

Fighting those cravings is life changing—literally.

Domino

 

Give a shoutout to Glen Carrie on social or copy the text below to attribute.

Sugar is a cruel, cruel mistress—it’s delicious and addictive, but it’s not doing you any favors. Aside from causing weight gain, increased consumption of refined sugar increases the risk of insulin resistance, type 2 diabetes, and cardiovascular disease, and can impact cognitive function and memory, says best-selling author Sara Gottfried, M.D.

It turns out your daily afternoon sugary treat not only gives you major brain fog—according to author David Wolfe, it also accelerates aging. 

It may seem daunting, even impossible, to remove processed sugar from your diet, but understanding all the extraordinary things that happen when you cut it out can empower you to kick the habit. Keep reading.

After an Hour

Expect withdrawals, even after a few hours. “Sugar is addictive and activates a dopamine response in the reward center of the brain, like a drug,” says Wolfe. Depending on the amount of sugar you consume daily, you might experience varying drops in blood sugar levels, sweating, shaking, irritable moodiness, hunger, and sadness. Gottfried suggests fighting through these symptoms by consuming fresh vegetables with fiber, anti-inflammatory protein sources, and healthy fats.

After a Day

02-26.jpg

The days just after you’ve stopped consuming sugar are perhaps the hardest. “You may have withdrawal-like symptoms including headaches and a drop in energy levels,” says Gottfried. You’ll probably have some strong cravings for something sweet, too.

But already, your body is beginning to heal itself. According to Wolfe, sugar feeds harmful microorganisms, such as candida—which, when overgrown, can affect your gut health. Cutting out processed sugar helps keep those microorganisms in check.

After a Week

03-24.jpg

This is when the magic happens. Your body will quickly start to repair itself once sugar is out of the way, starting with improvements in insulin levels and inflammatory responses. According to Gottfreid, in just 72 hours, as your insulin levels begin to stabilize, other hormones (like those involved in fat storage) will also return to normal levels. Another noticeable difference? Skin clarity and less puffiness in the face, says Wolfe.

After a Month

06-19.jpg

“You’ll realize what sugar has been doing to you, namely increasing cravings, causing weight gain and yeast infections, and amplifying inflammation,” says Wolfe. Why? Because a lot of these issues, as well as hankerings for treats, will be disappearing.

Add to those benefits stable blood sugar levels, improved mental clarity, natural weight loss, and improved gut health. “A healthy gut reduces inflammation in your body and your overall risk for many health problems,” says Gottfried.

After Six Months

07-17.jpg

Imagine this: “You will be so far away from the habit of eating sugar that you will not only not want it, but you won’t even be able to look at it,” says Wolfe. Gottfried adds that when you have stable blood sugar levels, you’ll find weight stays off, especially that stubborn belly fat. More important, you’ll be overall healthier: Six months without refined sugar will decrease your risk of type 2 diabetes, cardiovascular disease, and early aging, she says.

After a Year

08-16.jpg

On a surface level, skin quality and reduction of acne, irritation, and fine lines can be dramatic when sugar is eliminated from your daily diet. Even better, you will see a reduction in overall risk of preventable diseases, like diabetes, as well as heart attack and stroke. Not to mention, you’ll also increase your quality and length of life. Seriously—we’re not sugarcoating it.

 Kristin Limoges is the Wellness Editor at Domino.


Sunday, 23 August 2020

What Happens to Your Body When You Stop Eating Sugar

Sugar


Fighting those cravings is life-changing—literally.

Domino

01-26.jpg
Photography by Cody Guilfoyle.

Sugar is a cruel, cruel mistress—it’s delicious and addictive, but it’s not doing you any favors. Aside from causing weight gain, increased consumption of refined sugar increases the risk of insulin resistance, type 2 diabetes, and cardiovascular disease, and can impact cognitive function and memory, says best-selling author Sara Gottfried, M.D.
It turns out your daily afternoon sugary treat not only gives you major brain fog—according to author David Wolfe, it also accelerates aging. 
It may seem daunting, even impossible, to remove processed sugar from your diet, but understanding all the extraordinary things that happen when you cut it out can empower you to kick the habit. Keep reading.

After an Hour

Expect withdrawals, even after a few hours. “Sugar is addictive and activates a dopamine response in the reward center of the brain, like a drug,” says Wolfe. Depending on the amount of sugar you consume daily, you might experience varying drops in blood sugar levels, sweating, shaking, irritable moodiness, hunger, and sadness. Gottfried suggests fighting through these symptoms by consuming fresh vegetables with fiber, anti-inflammatory protein sources, and healthy fats.

After a Day

02-26.jpg

The days just after you’ve stopped consuming sugar are perhaps the hardest. “You may have withdrawal-like symptoms including headaches and a drop in energy levels,” says Gottfried. You’ll probably have some strong cravings for something sweet, too.
But already, your body is beginning to heal itself. According to Wolfe, sugar feeds harmful microorganisms, such as candida—which, when overgrown, can affect your gut health. Cutting out processed sugar helps keep those microorganisms in check.

After a Week

03-24.jpg


This is when the magic happens. Your body will quickly start to repair itself once sugar is out of the way, starting with improvements in insulin levels and inflammatory responses. According to Gottfreid, in just 72 hours, as your insulin levels begin to stabilize, other hormones (like those involved in fat storage) will also return to normal levels. Another noticeable difference? Skin clarity and less puffiness in the face, says Wolfe.

After a Month

06-19.jpg

“You’ll realize what sugar has been doing to you, namely increasing cravings, causing weight gain and yeast infections, and amplifying inflammation,” says Wolfe. Why? Because a lot of these issues, as well as hankerings for treats, will be disappearing.
Add to those benefits stable blood sugar levels, improved mental clarity, natural weight loss, and improved gut health. “A healthy gut reduces inflammation in your body and your overall risk for many health problems,” says Gottfried.

After Six Months

07-17.jpg

Imagine this: “You will be so far away from the habit of eating sugar that you will not only not want it, but you won’t even be able to look at it,” says Wolfe. Gottfried adds that when you have stable blood sugar levels, you’ll find weight stays off, especially that stubborn belly fat. More important, you’ll be overall healthier: Six months without refined sugar will decrease your risk of type 2 diabetes, cardiovascular disease, and early aging, she says.

After a Year

08-16.jpg

On a surface level, skin quality and reduction of acne, irritation, and fine lines can be dramatic when sugar is eliminated from your daily diet. Even better, you will see a reduction in overall risk of preventable diseases, like diabetes, as well as heart attack and stroke. Not to mention, you’ll also increase your quality and length of life. Seriously—we’re not sugarcoating it.
 Kristin Limoges is the Wellness Editor at Domino.

Thursday, 25 July 2019

Is Sweetness Your Weakness? A Dietitian’s Guide to Giving Up Sugar

Is Sweetness Your Weakness? A Dietitian’s Guide to Giving Up Sugar|


 Newswise: News for Journalists: How does the body react when you nix sugar from your diet? UNLV nutritionist Samantha Coogan shares a solution for withdrawal symptoms, and what to expect when they’re over.



Newswise — From birthday cakes to Thanksgiving pie to cold summer treats, every holiday, season or special occasion harkens mouth-watering memories of a favorite confectionery craving.
But what if you’re trying to get healthy by shutting down the sugar in your diet?

Samantha Coogan —  director of UNLV's Didactic Program in Nutrition & Dietetics and president of the Nevada Academy of Nutrition and Dietetics — explains how putting a halt on sweet treats affects the body.

How does the body react when you cease the sugar in your diet, and how long do symptoms last? 

When you cut out sugar, you'll be cutting out a boatload of empty, useless calories, which should help with weight loss  — as long as you don't replace those sugar calories with other empty calories!
Replacing sugar with things like fiber and protein will increase your satiety values, allowing you to feel fuller for longer while reducing your overall caloric intake. Sugar has a very low satiety value and causes sharp spikes and dips in blood sugar, causing you to feel that "shaky" sensation and almost ravenous levels of hunger soon after consumption.

Sugar is quite addictive, so some may experience withdrawal symptoms. It sounds silly, but it's true: When your body becomes accustomed to certain substances, removing that substance essentially leaves your body in a state of shock. It will cause some uncomfortable moments such as headaches, stomach upset, or disruption in bowel activity as your body starts to reset itself. Withdrawal symptoms could last anywhere from a few days to two week.

Once you get past the immediate withdrawal, what can you expect? 
Once you weather the initial withdrawal symptoms — if they even occur — your overall energy should improve in all areas of your life. For example, you may notice your:
  • Hair, skin and nails start to improve
  • Cravings change drastically (once you remove sugar for enough time, you start to miss it less and less)
  • Performance in the gym improves and you'll recover from workouts more quickly and potentially reduce your risk for injury
  • Productivity at work should improve and you'll need fewer sick days
  • Belly fat decreases because your body won't have any excess sugar to store as fat in your adipose tissue
  • Sleep cycles become longer and more consistent (sugar can negatively affect your REM sleep if your body is constantly searching for its next fix)
It may be a harsh comparison, but think about how drug addicts live on a day-to-day basis. Work is either low quality or non-existent; workouts are either minimal intensity, or again non-existent; and their sleep patterns are constantly disturbed without ever feeling fully rested. Sugar is an addictive substance for some people, so it really is necessary to approach it in a similar manner to drug/alcohol detoxification.

How do you get through the withdrawal stage without backsliding?
You can get through the withdrawals by upping your water intake, or by chewing on gum or snacking on fruit for a sweet sensation without all the artificial sugar. Just give your mind and mouth something else to think about when a sugar craving approaches.

Sugar often makes us feel lethargic, fatigued and begging for more, which also takes a toll on the body. Some people may feel the positive effects of a sugar-free diet right away, while others may take a little longer. If you experience withdrawal symptoms, you may not even realize the benefits that are happening at the same time during that two-week period.

When do these positive changes start?

Everyone’s body is different, but for some people it’s possible to start to see, taste and feel changes in as early as three days. Fruit may start to taste sweet again — almost like candy — because your taste receptors have been given a chance to relax and stop searching for that sugar. Your sweetness tolerance starts to reduce in only a few days as well. The higher your sugar tolerance was, the longer it may take for naturally sweetened foods to taste as sweet as before. You may even find that certain foods are almost too sweet for your new preference.

Again, every person and body is different. Many factors — such as genetics, presence of or risk factors for certain chronic diseases and conditions, physical activity level, carb/sugar sensitivity, age, gender — may play a role in how, and how long, your body reacts to the removal of sugar.

Thursday, 30 May 2019

4 Sugar Alternatives That Won't Poison You

Sugar Alternatives

This is very useful information for reducing sugar intake!


Views 138357
You may think that staying slim and eating healthfully means NO sweets, but guess what? There are natural and delicious sweeteners that won’t wreck your diet, and even have therapeutic 'side benefits.'
No arena of health and wellness is more debatable than what we should be eating. Looking back through time, the foods that constitute a healthy diet have changed so dramatically, you can literally mark the passage of time by the coming and going of dietary fads.
  • Weight-loss clubs and diet pill popping in the 1970s
  • Cabbage soup and liquid diets in the ‘80s
  • The Zone and blood-type diets (along with lawsuits related to diet pills!) in the ‘90s
  • In the aughts, Atkins and gluten-free
  • In the 2010’s, it’s Paleo, raw, and local
Despite this obsessive focus on what to eat, Americans are fatter and in many ways, unhealthier than ever before[1]. In 2016, two-thirds of the adult population were considered overweight or obese, according to a U.S. Dept. of Health and Human Services study[2]. This health epidemic spans ethnic and cultural boundaries, and is affecting more adults and children every year.
One factor that is contributing to America’s growing problem with weight is our obsession with sugar. You probably don’t need to see the results of a clinical study to believe that the more sugary calories you consume, the greater your risks of obesity[3]. What you may not know, is that what passes for sugar these days is actually a hyper-sweetened extract of one of the cheapest, most heavily-sprayed, GMO-pervasive crops on the planet.

Why Sugar Isn’t Sugar Anymore

Despite a marked decrease in consumption of refined cane and beet sugars over the last generation, we are taking in more dietary sugar overall, thanks to the prevalence of corn-based sweeteners like high-fructose corn syrup, in nearly everything on grocery store shelves[4].

Switching to corn-based sweeteners is a case of jumping from the funnel cake grease into the fire! Corn syrup has become the go-to sweetening agent for processed foods due to its low cost and high concentration (at least 1.5 times that of cane sugar). Thanks to government subsidies, corn is alluringly cheap for food and beverage companies that need a steady supply of sweetness.
Corn is also a top GMO crop with at least 92% of the nation’s corn supply being genetically modified to withstand large doses of herbicides[5]. Setting aside the shocking effects of GMO consumption, this intense concentration of simple sugar is wreaking havoc on the collective metabolism. Studies abound correlating intake of high-fructose sweeteners to increased risks of obesity, cardiovascular disease, hypertension, fatty liver disease, diabetes, and more[6].

What About Zero-Calorie Sweeteners?

Aspartame, Equal, sucralose, Splenda, saccharin: they go by many names but do any of them sound truly sweet? Not when you read the nearly 100 scientific abstracts Greenmedinfo has collected on the perils of artificial sweeteners. Chemical fascimiles of sugar, these unnatural compounds can be far worse than the real thing.
Linked to increased risks of kidney disease, metabolic dysfunction, diabetes, and obesity, these calorie-free sugar substitutes trick consumers into thinking that previously unhealthy foods can get “a sugar-free pass.” But fake sugars are far from harmless. Studies show consuming synthetic sweeteners generates excessive cravings for the sweet taste, leading to weight gain and other negative effects linked to excessive sugar consumption[7].
While it might be tempting to think that these sugar imposters can help you bypass the weight and still eat the treats, if you value your health, steer clear of these dietary destroyers!

Nature Has the Solutions

Wondering what options this leaves you when only something sweet will do? Fortunately, nature has got you covered. Here are four solutions for satisfying your sweet tooth that won’t rot your teeth, create blood sugar imbalance, or cause weight gain. In fact, these natural wonders pack some amazing health benefits!

Xylitol

Xylitol is a sugar alcohol derived from xylose - a crystalline sugar found in birch bark[8]. Sweet like sugar but with only 40% of the calories, xylitol is fast becoming the preferred sweetener of health-conscious consumers.
Low-carb dieters will find xylitol appealing, with less than a quarter of the carbohydrates found in cane sugar. It also stands apart from synthetic sweeteners thanks to its natural origins. Besides birch trees, xylitol is found in the cellular structure of fruits like raspberries, and in vegetables like the corn-cob. Even our bodies produce xylitol (between 5-15 grams per day) during normal metabolic processes.
With a glycemic rating of 13, xylitol is metabolized around eight times slower than regular sugar, making it a safer choice for diabetics. Unlike sugar, which provokes the release of insulin in response to its consumption, xylitol is metabolized independently of insulin in the gut. It metabolizes slower and steadier than sugar, making it a much safer sweetener for hypoglycemics and the sugar-sensitive.
And there’s good news for sufferers of cavities or Candida: Xylitol actually discourages the bacterial growth that feeds these conditions. The bacteria that cause candida, dental caries, and even Streptococcus mutans, thrive in acid-based environments, with sugar as their food of choice. Xylitol is non-fermentable, creating an alkaline reaction in the body that bacteria find inhospitable. Xylitol consumption has been shown to dramatically decrease cavities and ear and throat infections, among other infectious organisms.
The dental health community are one of the biggest supporters of Xylitol. Studies have shown that plaque build-up and dental caries can be reduced by 80% with the introduction of moderate amounts of xylitol (up to  half an ounce per day). Research also indicates that consuming  xylitol may increase bone strength and bone density.
*Important Notes: Xylitol can have a laxative effect, so start slowly. It is best to obtain Xylitol from a manufacturer who uses birch rather than corn. Finally, Xylitol is extremely toxic to dogs, so please keep it away from Fido! Xylitol is sometimes made from corn, which includes GMO corn. Look for the higher quality, non-GMO certified, and best of all: birch tree derived form.

Stevia

300 times sweeter than sugar and without caloric content, the Stevia plant has been used by native people to sweeten food and drink for centuries. Stevia’s popularity as a modern sugar substitute grew in the 1990’s, and new research confirms what tribal cultures knew: this plant provides a safe, affordable and tasty alternative to expensive and potentially dangerous sweeteners.
The study[9], published in August 2017, calls Stevia “a suitable calorie-free sweetener,” with both “pharmacological and therapeutic properties, including antioxidant, antimicrobial, antihypertensive, antidiabetic, and anticancer.” Researchers further heralded Stevia’s positive effects on those metabolic conditions aggravated by excess sugar consumption, namely obesity, hypertension, and diabetes.
Stevia reduces blood sugar, reduces blood pressure, combats infections, and reduces risks of diabetes. One study even found that consuming stevia was as effective as a popular oral antidiabetic drug, but with fewer side effects.
If you haven’t tried Stevia in a while, you will be pleasantly surprised by new formulations. What began as a strong-tasting plant extract only available in health food stores, is now widely available in crystallized-sugar form, as a finely distilled concentrate, and in formulations that approximate the less-sweet taste of cane sugar, but without the negative effects!

Raw Honey

Identified as containing more than 181 health-promoting substances[10], honey converts the vital, healing energy of plants into a medium that is perfect for human consumption. Rich in phytonutrients (nutrients absorbed from plants), raw honey is renowned worldwide for having powerful anti-oxidative and anti-inflammatory properties[11].
Raw, unfiltered honey is very different from the pasteurized product you find on most grocery store shelves. Nearly all commercially-produced honey is heated to kill potentially harmful bacteria, reduce crystallization, and improve product flow. Unfortunately, this process also kills the vital, living enzymes and good bacteria which make raw honey one of the world’s oldest-known superfoods.
The bacteria in raw honey serves as a prebiotic: a substance containing helpful microorganisms that aid in the process of digestion. When consumed raw, honey’s natural enzymes aid in the breakdown and assimilation of the many nutrients it contains.
Raw honey is also rich in powerful antioxidants called phenolic compounds, known to play an important role in cancer prevention[12].  These compounds found in honey have also shown promise in reducing arterial blockages and lowering overall risks associated with cardiovascular disease[13].
Perhaps most profound of all is that raw honey contains probiotic strains that are so ancient that one form of Lactobacillus present with certain varieties is believed to be of a lineage 80 million years old. Learn more:  Could Eating Honey Be A Form of Microbial Time Travel?

Molasses

Blackstrap molasses, known to sugar-refiners as “final molasses,” refers to the thick, brown syrup that is the end result of boiling sugar cane during the production of table sugar. What sets molasses apart from cane sugar, besides the obvious appearance, is its high nutritional value. Unlike its nutritionally bankrupt cousin, a 3.5 oz serving of blackstrap molasses contains more than a quarter of your daily supply of vital minerals such as iron, magnesium, potassium, manganese, and B vitamins[14]. Molasses delivers this nutritional punch with much less sugar, thanks to being at the end of the line of the crystalline-sugar extraction process[15].
Molasses has long been a popular folk remedy, treating everything from menstrual cramps to constipation[16]. An old wives’ tale credits an elixir of molasses and milk with having the power to maintain endless youth and beauty. There may be some truth to this, thanks to molasses’ high antioxidant content[17]. Polyphenols, the plant compounds that imbue antioxidant properties, are abundant in molasses, and have been recognized for having anti-cancer properties[18] in clinical studies.
A 2011 study showed that adding molasses to a high-fat diet had the effect of reducing body weight and body fat percentages, thanks to decreased calorie absorption. Researchers concluded that “supplementing food with molasses extract might be a way to address the escalating rates of overweight and obesity."[19]
Rich in copper, iron, and calcium, molasses can play a vital role in maintaining healthy blood and bones. This makes molasses a great alternative to non-nutritive sweeteners for pregnant or nursing women, or women who are trying to become pregnant. It also makes a great dietary supplement for women at risk of developing osteoporosis.
These four, healthful alternatives to sugar prove that craving a taste of sweetness doesn’t have to cause cavities, promote weight gain, or lead to blood sugar imbalances. On the contrary, when we look to nature, we find natural foods which actually sweeten our health, as well as our palates.

References


[1] https://www.cdc.gov/nchs/data/nhis/earlyrelease/Earlyrelease201705_06.pdf
[2] https://www.niddk.nih.gov/health-information/health-statistics/overweight-obesity
[3] https://www.ncbi.nlm.nih.gov/pubmed/23321486
[4] http://www.pewresearch.org/fact-tank/2016/12/13/whats-on-your-table-how-americas-diet-has-changed-over-the-decades/ft_16-12-09_food_more_less/
[5] http://www.centerforfoodsafety.org/issues/311/ge-foods/about-ge-foods#
[6] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477723/
[7] http://care.diabetesjournals.org/content/32/4/688
[8] https://www.merriam-webster.com/dictionary/xylitol
[9] https://www.ncbi.nlm.nih.gov/pubmed/28792778
[10] White JW. Composition of honey. In: Crane E, editor. Honey, a comprehensive survey. London: Bee research Association and Chalfont St Peter; 1975. pp. 157–206.
[11] https://www.livescience.com/52541-phytonutrients.html
[12] https://www.ncbi.nlm.nih.gov/pubmed/20043255
[13] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005390/?tool=pubmed
[14] https://en.wikipedia.org/wiki/Molasses
[15] http://www.sciencedirect.com/topics/medicine-and-dentistry/sugarcane-juice
[16] http://journals.lww.com/pec-online/Abstract/2011/12000/Safety_and_Efficacy_of_Milk_and_Molasses_Enemas.3.aspx
[17] https://www.ncbi.nlm.nih.gov/pubmed/19103324
[18] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC305362/#B31
[19] https://www.sciencedaily.com/releases/2011/07/110712094038.htm
Originally published: 2017-09-11
Article updated: 2019-05-29
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of GreenMedInfo or its staff.

Wednesday, 5 September 2018

New Splenda Studies Confirm Its Dangers

The Dangers Of Artificial Sweeteners

 Here we are again, believing that the alternative to sugar in our beverages are healthy only to be proved wrong.

Story at-a-glance

  • The artificial sweetener industry has defended the safety of sucralose (Splenda), stating that it rapidly passes unmetabolized through your body and therefore has no biological effects
  • Recent research reveals sucralose is in fact metabolized and that it accumulates in your fat cells. The study found two new metabolites that have not previously been identified
  • As these findings were not part of the original regulatory decision process for sucralose, the researchers are calling for a review of its safety and regulatory status
  • Other recent research found sucralose causes definite changes in the liver of treated rats, suggesting toxic effects. According to the researchers, sucralose should be used with caution to avoid liver damage
  • Previous research found sucralose reduces gut bacteria by 50 percent, preferentially targeting bacteria known to have important human health benefits
  •  
  •  
    By Dr. Mercola
    Sucralose (sold under the brand name Splenda) was approved by the U.S. Food and Drug Administration (FDA) in 1998 as a tabletop sweetener and for use in products such as baked goods, nonalcoholic beverages, chewing gum, frozen dairy desserts, fruit juices and gelatins.
    It's also permitted as a general-purpose sweetener for processed foods. (In the European Union, sucralose is known under the additive code E955.) The approval was given after the FDA supposedly reviewed more than 110 animal and human safety studies, but of these 110 studies, only two were done on humans, and the longest one lasted just four days.
    I knew the approval of sucralose was a nearly identical mistake that the FDA made with aspartame, which is why I wrote my book, "Sweet Deception," in 2006, despite the fact Johnson & Johnson threatened to sue me if I published it. It is certainly vindicating to see the studies confirm what I wrote about in my book over 12 years ago.
    Artificial sweeteners like aspartame and sucralose may have zero calories, but your body isn't fooled. When hit with a "sweet" taste, your body expects calories to follow, and when this doesn't happen, it causes biochemical distortions that can result in weight gain, metabolic dysfunction and other health problems.

    Sucralose Decimates Your Gut Microbiome

    Different artificial sweeteners have been found to wreak havoc in a number of different ways. Aspartame, for example, has a long list of studies detailing harmful effects ranging from brain damage to preterm delivery. Sucralose, meanwhile, has been found to be particularly damaging to your gut. Research1 published in 2008 found sucralose:
    • Reduces gut bacteria by 50 percent, preferentially targeting bacteria known to have important human health benefits (consuming as few as seven little Splenda packages is enough to have a detrimental effect on your microbiome)
    • Increases the pH level in your intestines
    • Is absorbed into and accumulates in fat tissue
    In response to this study, James Turner, chairman of the national consumer education group Citizens for Health issued the following statement:2
    "The report makes it clear that the artificial sweetener Splenda and its key component sucralose pose a threat to the people who consume the product. Hundreds of consumers have complained to us about side effects from using Splenda and this study ... confirms that the chemicals in the little yellow package should carry a big red warning label."

    New Study Finds Sucralose Is Metabolized and Stored in Your Body

    Needless to say, the industry has vehemently defended sucralose (and all other chemical sweeteners), stating that it rapidly passes unmetabolized through your body and therefore has no biological effects. Alas, recent research has punched yet another giant hole in the argument that sucralose is a biologically inert chemical, showing it is in fact metabolized and that it accumulates in fat cells.
    The study3,4 in question was published in the online version of the Journal of Toxicology and Environmental Health August 21, 2018. An interview with the authors can be found on Inverse.5
    Ten rats were given an average dose of 80.4 milligrams (mg) of sucralose per kilo per day (k/day) for 40 days. According to the researchers, this dosage is "within the range utilized in historical toxicology studies submitted for regulatory approval in North America, Europe and Asia."
    Urine and feces were collected daily from each rat, and were analyzed using ultrahigh performance liquid chromatography tandem mass spectrometry (UHPLC–MS/MS), which "revealed two new biotransformation products that have not previously been reported."

    Research Calls for New Safety Review of Sucralose

    The two metabolites are acetylated forms of sucralose that are lipophilic, meaning they dissolve in and combine with fats. Sucralose itself is far less lipophilic, which has been part of the safety argument. According to the authors:
    "These metabolites were present in urine and feces throughout the sucralose dosing period and still detected at low levels in the urine 11 days after discontinuation of sucralose administration and six days after sucralose was no longer detected in the urine or feces.
    The finding of acetylated sucralose metabolites in urine and feces do not support early metabolism studies, on which regulatory approval was based, that claimed ingested sucralose is excreted unchanged (i.e., not metabolized).
    The historical metabolic studies apparently failed to detect these metabolites in part because investigators used a methanol fraction from feces for analysis along with thin layer chromatography and a low-resolution linear radioactivity analyzer.
    Further, sucralose was found in adipose tissue in rats two weeks after cessation of the 40-day feeding period even though this compound had disappeared from the urine and feces."
    So, not only is sucralose metabolized, these metabolites accumulate in your fat tissues, where they remain for "an extended period of time" after you stop consuming sucralose. In all, these findings led the authors to conclude:
    "These new findings of metabolism of sucralose in the gastrointestinal tract and its accumulation in adipose tissue were not part of the original regulatory decision process for this agent and indicate that it now may be time to revisit the safety and regulatory status of this organochlorine artificial sweetener."

    Sucralose Is Not an Inert Compound

    Previous research has also noted that sucralose is not a biologically inert compound, as claimed. In the 2013 paper,6 "Sucralose, a Synthetic Organochloride Sweetener: Overview of Biological Issues," the authors state, in part:
    "Sucralose and one of its hydrolysis products were found to be mutagenic at elevated concentrations in several testing methods … Both human and rodent studies demonstrated that sucralose may alter glucose, insulin and glucagon-like peptide 1 levels. Taken together, these findings indicate that sucralose is not a biologically inert compound."
    Importantly, the study also notes that "Cooking with sucralose at high temperatures … generates chloropropanols, a potentially toxic class of compounds." Yet, Splenda is frequently recommended for cooking and baking,7 and is often used in processed foods in which high heat was involved.
    Chloropropanols, which are still poorly understood, are thought to have adverse effects on your kidneys and may have carcinogenic effects.8 However, it's worth noting that chloropropanols are part of a class of toxins known as dioxins, and dioxins are known to cause cancer and endocrine disruption.

    Sucralose May Cause Liver Damage With Regular Use, and More

    Another study9 published online August 2, 2018, in the journal Morphologie, found sucralose caused "definite changes" in the liver of treated rats, "indicating toxic effects on regular ingestion." According to these researchers, their findings suggest "sucralose would be taken with caution to avoid hepatic damage."
    In other words, regularly using Splenda could damage your liver. Here, adult rats were given a much higher (yet nonlethal) oral dose of sucralose — 3 grams (3,000 milligrams) per kilo body mass per day for 30 days, after which the animals' livers were dissected and compared to the livers of unexposed controls. According to the authors:
    "Experimental rats showed features of patchy degeneration of hepatocytes along with Kupffer cells hyperplasia, lymphocytic infiltration, sinusoidal dilatation and fibrosis indicating a definite hepatic damage on regular ingestion of sucralose. Sinusoidal width was also found to be increased in experimental animals as compared to controls."
    Studies have also linked sucralose consumption to:
    Genotoxicity (DNA damage) and potentially adverse epigenetic effects.10 According to this paper, the acceptable daily intake set for sucralose may in fact be hundreds of times too high to ensure safety
    Shrinkage of the thymus, up to 40 percent11,12
    Enlargement of the liver and kidneys13,14
    Calcification of the kidneys15,16
    Increased leukocyte populations (immune system cells) in the thymus and lymph nodes17
    Migraines18
    Altered glucose, insulin and glucagon-like peptide-1 levels and responses,19 which raises your risk for Type 2 diabetes.
    A study20 published in the journal Diabetes Care confirmed that, compared to controls, obese patients using sucralose experienced a greater incremental increase in peak plasma concentrations of glucose, a greater incremental increase in insulin and peak insulin secretion rate, along with a decrease in insulin clearance.
    According to the authors, "These data demonstrate that sucralose affects the glycemic and insulin responses to an oral glucose load in obese people who do not normally consume non-nutritive sweeteners"
    Alterations in P-glycoprotein (P-gp) levels, which could result in medications used in chemotherapy, AIDS treatment and treatments for heart conditions being shunted back into the intestines, rather than being absorbed by your body21

    Commonly Reported Side Effects of Splenda

    If you start searching for adverse events reports, you'll find scores of people reporting a variety of side effects from using Splenda. The following are common symptoms, usually noticed within a 24-hour period following consumption of a Splenda product:
    Skin — Redness, itching, swelling, blistering, weeping, crusting, rash, eruptions or hives (itchy bumps or welts)
    Lungs — Wheezing, tightness, cough or shortness of breath
    Head — Swelling of the face, eyelids, lips, tongue, or throat; headaches and migraines (severe headaches)
    Nose — Stuffy nose, runny nose (clear, thin discharge), sneezing
    Eyes — Red (bloodshot), itchy, swollen or watery
    Stomach — Bloating, gas, pain, nausea, vomiting, diarrhea or bloody diarrhea
    Heart — Palpitations or fluttering
    Joints — Joint pains or aches
    NeurologicalAnxiety, dizziness, spaced-out sensation, depression

    Are You Having a Reaction to Splenda?

    To determine if you're having a reaction to artificial sweeteners — be it Splenda, aspartame or any of the others — take the following steps:
    1. Eliminate all artificial sweeteners from your diet for two weeks
    2. After two weeks, reintroduce your artificial sweetener of choice in a significant quantity (about three servings daily)
    3. Avoid other artificial sweeteners during this period
    4. Do this for one to three days and take notice of how you feel, especially as compared to when you were abstaining from artificial sweeteners
    5. If you don't notice a difference in how you feel after reintroducing your primary artificial sweetener for a few days, it's a safe bet you're able to tolerate it acutely, meaning your body doesn't have an immediate, adverse response. Just know that this doesn't mean your health won't be damaged in the long run
    6. If you've been consuming more than one type of artificial sweetener, repeat steps 2 through 4 with the next sweetener on your list
    If you do experience side effects from an artificial sweetener (or any other food additive for that matter), please report it to the FDA (if you live in the U.S.). It's easy to make a report — just go to the FDA Consumer Complaint Coordinator page, find the phone number for your state, and make a call to report your reaction.
    Keep in mind that some medications may contain sucralose as well, even if it's not listed on the label. If you continue to experience any of the symptoms above even though you're avoiding Splenda and other artificial sweeteners, then it may be worth investigating whether any of the medications you're taking contain artificial sweeteners.

    Splenda Has Never Been Proven Safe for Human Consumption

    The FDA claims they reviewed over 100 studies conducted on Splenda. What they don't tell you is that a) only six of these studies were human trials — and only two of them were published before the FDA approved sucralose for human consumption — and b) the remaining animal studies actually revealed potential health problems, including:22
    • Decreased red blood cells (a sign of anemia) at levels above 1,500 mg/kg/day
    • Increased male infertility by interfering with sperm production and vitality, as well as brain lesions at higher doses
    • Spontaneous abortions in nearly half the rabbit population given sucralose, compared to zero aborted pregnancies in the control group
    • A 23 percent death rate in rabbits, compared to a 6 percent death rate in the control group
    What's more, the two human trials had a grand total of 36 subjects, only 23 of whom were actually given sucralose, and the longest of these trials lasted just four days and looked at sucralose in relation to tooth decay, not human tolerance.23
    Even more shocking, the absorption of Splenda into the human body was studied on a grand total of six men. Based on that study,24 the FDA allowed the findings to be generalized as being representative of the entire human population, including women, children, the elderly and those with any chronic illness — none of whom were ever examined.

    Healthier Sugar Substitutes

    Two of the best sugar substitutes are from the plant kingdom: Stevia and Lo Han Kuo (also spelled Luo Han Guo). Stevia, a highly sweet herb derived from the leaf of the South American stevia plant, is sold as a supplement. It's completely safe in its natural form and can be used to sweeten most dishes and drinks.
    Lo Han Kuo is similar to Stevia, but it's a bit more expensive and harder to find. In China, the Lo Han fruit has been used as a sweetener for centuries, and it's about 200 times sweeter than sugar. A third alternative is to use pure glucose, also known as dextrose.
    Dextrose is only 70 percent as sweet as sucrose, so you'll end up using a bit more of it for the same amount of sweetness, making it slightly more expensive than regular sugar. Still, it's well worth it for your health as it does not contain any fructose whatsoever. Contrary to fructose, glucose can be used directly by every cell in your body and as such is a far safer sugar alternative.
    + Sources and References